Dicyclanil

NOMENCLATURE
Common name dicyclanil (pa ISO)
IUPAC name 4,6-diamino-2-cyclopropylaminopyrimidine-5-carbonitrile
Chemical Abstracts name 4,6-diamino-2-(cyclopropylamino)-5-pyrimidinecarbonitrile
CAS RN [112636-83-6] Development codes CGA 183893 (Ciba-Geigy)

PHYSICAL CHEMISTRY
Mol. wt. 190.2 M.f. C8H10N6 V.p. <2 ´ 10-8 mPa (20 °C) KOW logP = 2.9 S.g./density 1.57 (21 °C) Solubility In water 50 g/l (pH 7.2, 25 °C). In methanol 4.9 g/l (25 °C). Stability Hydrolysis DT50 331 d (pH 3.8), >1 y (pH 6.9) (both 25°C).

COMMERCIALISATION
History Reported by H. Kristinsson (Proc. 8th IUPAC Int. Congr. of Pestic. Chem., Washington, 1994). Developed by Ciba-Geigy AG (became Novartis Crop Protection AG); transferred to Novartis Animal Health. Manufacturers Novartis A H

APPLICATIONS
Mode of action Interferes with moulting. When incorporated into the insect breeding substrate, prevents the development of larvae into pupae or adults. Uses Insect growth regulator, with a high specificity against Diptera and Siphonaptera. Used for control and prevention of blowfly strikes in sheep (1-2 ml/kg 5% suspension).